Methylcobalamin (Mecobalamin)
Methylcobalamin is an active, naturally occurring coenzyme form of Vitamin B12. It plays a critical role in transmethylation micro-reactions, nucleic acid synthesis, and the maintenance of the myelin sheath in the nervous system.
Dosage by Body Weight
Adult dose is typically 500 mcg to 1500 mcg daily in divided doses. Pediatric dosing is highly specific and must be determined by a pediatrician based on clinical deficiency levels.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in neonates are not fully established. Consult a pediatrician.
- Body Weight
- 5-7 kg
- Dose
- 50 mcg to 100 mcg
- Frequency
- Once daily
- Tracking Notes
- Administer only if diagnosed with nutritional deficiency or metabolic disorder.
- Body Weight
- 8-10 kg
- Dose
- 100 mcg to 150 mcg
- Frequency
- Once daily
- Tracking Notes
- To be given as oral drops or syrup under medical supervision.
- Body Weight
- 11-15 kg
- Dose
- 150 mcg to 250 mcg
- Frequency
- Once daily
- Tracking Notes
- Adjust dosage based on serum B12 levels.
- Body Weight
- 16-20 kg
- Dose
- 250 mcg to 500 mcg
- Frequency
- Once daily
- Tracking Notes
- Tablet (dispersible) or syrup formulation may be used.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in neonates are not fully established. Consult a pediatrician. |
| 5-7 kg | 50 mcg to 100 mcg | Once daily | Administer only if diagnosed with nutritional deficiency or metabolic disorder. |
| 8-10 kg | 100 mcg to 150 mcg | Once daily | To be given as oral drops or syrup under medical supervision. |
| 11-15 kg | 150 mcg to 250 mcg | Once daily | Adjust dosage based on serum B12 levels. |
| 16-20 kg | 250 mcg to 500 mcg | Once daily | Tablet (dispersible) or syrup formulation may be used. |
Formulation
Purpose
Used to treat Vitamin B12 deficiency, peripheral neuropathy, diabetic neuropathy, and megaloblastic anemia.
Generic Name
MethylcobalaminBranded Drug Names
Methylcobalamin (Mecobalamin) is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
No. This medicine is generally not treated as a scheduled/prescription-only drug in common consumer references, but local rules may vary.